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Wuhan Grand Hoyo Co., Ltd., has been approved the latest GMP by China State Food and Drug Administration National in Chinese amino acid industry, currently has production licenses for Acetyltyrosine，Acetylcysteine, Cysteine Hydrochloride，Carbocisteine，Arginine Hydrochloride，Histidine Monohydrochloride, and Lysine Hydrochloride.
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Arginine And Its Derivatives There Are Mainly the Following Types
L-Citrulline DL-Malate 2:1 Animal
L-Citrulline DL-Malate 2:1 (Animal source) is the product which mixed by L-Citrulline(Animal source) and DL-Malate.Usage: It is widely used in drugs, nutrition and health products, health functional foods, food supplements, whitening and beauty products, cosmetics, etc.
L-Ornithine L-Aspartate Animal
L-Ornithine L-Aspartate Animal Source is very soluble in water and almost insoluble in methanol or ethanol. When the product enters the human body, it is decomposed into aspartic acid and ornithine.
L-Ornithine HCl Non-Animal
L-Ornithine HCl(Non-animal Source) is one of the products of the action of the enzyme arginase on L-arginine, creating urea. Therefore, ornithine is acentral part of the urea cycle, which allows for the disposal of excess nitrogen.
L-Ornithine HCl Animal
L-Ornithine HCl is one of the products of the action of the enzyme arginase on L-arginine, creating urea. Therefore, ornithine is acentral part of the urea cycle, which allows for the disposal of excess nitrogen. Ornithine is recycled and, in a manner, is a catalyst.
L-Arginine L-Aspartate Animal
L-Arginine L-Aspartate is one of the 20 amino acids that build up protein. L-Arginine L-Aspartate is one of the non-essential amino acids, meaning it can be synthesised in the body. L-Arginine L-Aspartate is a precursor of nitric oxide and other metabolites.
L-Citrulline Animal
L-Citrulline Animal is obtained as a result of a reaction of L-arginine (ex duck feather) hydrochloride with sodium hydroxide, copper oxide and hydrogen sulfide.
Advantages of Arginine And Its Derivatives
1. L-Arginine L-Aspartate Animal
Athletic performance enhancement
Limited evidence suggests that L-arginine L-aspartate supplements may enhance exercise performance by increasing nitric oxide in the body, which improves blood flow and oxygenation to muscles.
Blood pressure regulation
L-arginine supplements may benefit those with high blood pressure.Studies have shown that taking L-arginine L-aspartate supplements may help lower both your systolic (the top number) and diastolic (the bottom number) blood pressure readings.L-arginine is needed for the production of nitric oxide, which is necessary for the relaxation of the cells that make up blood vessels, as well as blood pressure regulation.
Management of critical illness
L-arginine L-aspartate becomes essential when your body is compromised due to conditions like infection and trauma, and your L-arginine L-aspartate needs significantly increase due to physiologic demands.Under these circumstances, your body can no longer fulfill your arginine needs, which must be met through external sources.Arginine depletion during critical illness or after surgery leads to serious adverse effects, including impaired immune function and blood flow. To avoid these potential complications, arginine supplements are used frequently in the clinical setting to treat a variety of conditions.
Blood sugar regulation
Research shows that L-arginine L-aspartate may benefit those with diabetes by improving glucose metabolism and insulin sensitivity.L-arginine L-aspartate is needed for the production of nitric oxide. Nitric oxide plays important roles in cellular function and how your body responds to insulin, a hormone that shuttles blood sugar from your blood into cells, where it’s used for energy.
2. L-Citrulline Animal
Enhanced Exercise Performance
L-citrulline has also been shown to improve oxygen uptake kinetics and exercise performance during high-intensity activities. L-citrulline supplementation lowers the mean response time of oxygen uptake during severe-intensity exercise and increases the total amount of work completed. This suggests that L-citrulline can enhance endurance and performance in high-intensity workouts.
Blood Pressure and Vascular Function
L-citrulline is effective in improving cardiovascular health by enhancing nitric oxide production, which helps in vasodilation and blood flow. L-citrulline supplementation can lower blood pressure in adults with pre-hypertension and hypertension. It has been found to improve splanchnic perfusion and reduce gut injury during strenuous exercise, which can be beneficial for athletes5.
Endothelial Function in Older Adults
In older adults, L-citrulline supplementation has been linked to improved vascular function and muscle protein synthesis, potentially mitigating age-associated cardiovascular diseases and sarcopenia. This makes L-citrulline a promising supplement for maintaining cardiovascular health in aging populations.
Fetal Growth and Protein Synthesis
In animal models, L-citrulline supplementation has been shown to enhance fetal growth and muscle protein synthesis in cases of intrauterine growth restriction (IUGR). This indicates that L-citrulline can stimulate protein synthesis and support growth in conditions of undernutrition.
Immune Function and Oxidative Damage
L-citrulline has also been found to alleviate oxidative damage and immune dysfunction caused by iron overload in the thymus. It reduces iron deposition and enhances antioxidative capacity, thereby protecting against oxidative stress and inflammation9.